P0300 Ford F-150
Random/Multiple Cylinder Misfire Detected · Powertrain Code · High · Repair: Moderate
What is P0300?
The ECM has detected misfires occurring in multiple or random cylinders. Common causes include worn spark plugs, faulty ignition coils, vacuum leaks, low fuel pressure, or a failing catalytic converter.
When the Ford F-150 triggers code P0300 (random/multiple cylinder misfire detected), it typically points to an issue in the powertrain system. This is a high severity code, so address it promptly to avoid further damage or safety concerns. Below you'll find the most common causes, symptoms, and repair options specific to the Ford F-150.
This repair is rated moderate, meaning some experience and specialty tools required.
Diagnostic data on this page is compiled from publicly available repair resources and technical service bulletins. Always have a qualified mechanic confirm the diagnosis before authorizing repairs on your Ford F-150.
Common Causes on Ford F-150
- Coil-on-plug ignition coil failure common on 5.0L Coyote and 3.5L EcoBoost V6
- Spark plug ejection from cylinder head due to stripped threads (2004-2008 5.4L Triton)
- Carbon buildup on intake valves from direct injection on 3.5L and 2.7L EcoBoost
- Cam phaser rattle and timing chain wear causing VCT-related misfires on 5.0L Coyote (2018+)
- Fuel injector tip fouling from low-quality fuel on EcoBoost engines
Symptoms
- Rough idle with noticeable engine vibration
- Engine shaking or stumbling under load
- Loss of power during acceleration
- Check engine light flashing intermittently
- Poor fuel economy
- Hesitation or stumble on acceleration
Notes for Ford F-150
The 5.0L Coyote cam phaser issue has a TSB and extended warranty coverage on some model years.